7KN6
Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Spike protein S1 | polymer | 231 | 26095.3 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | C | VHH V | polymer | 135 | 14478.8 | 1 | Vicugna pacos | ||
| 3 | H | CC12.3 Fab heavy chain | polymer | 220 | 23377.2 | 1 | Homo sapiens (human) | ||
| 4 | L | CC12.3 Fab light chain | polymer | 214 | 23344.9 | 1 | Homo sapiens (human) | ||
| 5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ser 542 | - | expression tag |
| Gly 543 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87296.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 87517.4 |
