7KN5
Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Spike protein S1 | polymer | 231 | 26095.3 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
2 | C, D | VHH E | polymer | 129 | 14109.5 | 2 | Vicugna pacos | ||
3 | E, F | VHH U | polymer | 126 | 13700.0 | 2 | Vicugna pacos | ||
4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | A, C, E | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
6 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
7 | water | water | 18.0 | 415 | Chemie (HOH) |
Sequence modifications
A, B: 319 - 541 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Ser 542 | - | expression tag |
Gly 543 | - | expression tag |
His 544 | - | expression tag |
His 545 | - | expression tag |
His 546 | - | expression tag |
His 547 | - | expression tag |
His 548 | - | expression tag |
His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 107809.7 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 531.5 | |
All* | Total formula weight | 108765.6 |