7KN3
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Spike protein S1 | polymer | 231 | 26095.3 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
2 | H, M | S-B8 Fab heavy chain | polymer | 219 | 23225.9 | 2 | Homo sapiens (human) | ||
3 | L, N | S-B8 Fab light chain | polymer | 221 | 24271.9 | 2 | Homo sapiens (human) | ||
4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | A, H, M, N | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
6 | H, L | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
7 | L | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
8 | water | water | 18.0 | 441 | Chemie (HOH) |
Sequence modifications
A, B: 319 - 541 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Ser 542 | - | expression tag |
Gly 543 | - | expression tag |
His 544 | - | expression tag |
His 545 | - | expression tag |
His 546 | - | expression tag |
His 547 | - | expression tag |
His 548 | - | expression tag |
His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 147186.5 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1431.4 | |
All* | Total formula weight | 148617.9 |