7KN0
Structure of the integrin aIIb(W968V)b3 transmembrane complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-IIb | polymer | 43 | 4753.9 | 1 | UniProt (P08514) Pfam (PF00357) | Homo sapiens (Human) | GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb |
| 2 | B (B) | Integrin beta-3 | polymer | 44 | 4775.9 | 1 | UniProt (P05106) | Homo sapiens (Human) | Platelet membrane glycoprotein IIIa,GPIIIa |
Sequence modifications
A: 957 - 998 (UniProt: P08514)
B: 685 - 727 (UniProt: P05106)
| PDB | External Database | Details |
|---|---|---|
| Gly 956 | - | expression tag |
| Cys 962 | - | insertion |
| Gly 963 | Ala 994 | engineered mutation |
| Val 968 | Trp 999 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 684 | - | expression tag |
| Ser 686 | Cys 713 | engineered mutation |
| Cys 689 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 9529.7 | |
| All* | Total formula weight | 9529.7 |
