7KMW

Crystal structure of IspD from Mycobacterium paratuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	polymer	257	26224.9	4	UniProt (Q743W5) Pfam (PF01128)	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	4-diphosphocytidyl-2C-methyl-D-erythritol synthase,MEP cytidylyltransferase,MCT
2	E, F, G, H, I... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
3	Q, R, S, T (A, B, C, D)	water	water		18.0	228	Chemie (HOH)

Sequence modifications

A, B, C, D: 16 - 249 (UniProt: Q743W5)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag
Gly 2	-	expression tag
Thr 3	-	expression tag
Leu 4	-	expression tag
Glu 5	-	expression tag
Ala 6	-	expression tag
Gln 7	-	expression tag
Thr 8	-	expression tag
Gln 9	-	expression tag
Gly 10	-	expression tag
Pro 11	-	expression tag
Gly 12	-	expression tag
Ser 13	-	expression tag
Met 14	-	expression tag
Leu 15	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	104899.7
Non-Polymers*	Number of molecules	12
	Total formula weight	744.8
All*	Total formula weight	105644.5

*Water molecules are not included.