7KLU

Tetrameric human mitochondrial Hsp90 (TRAP1) in the presence of AMP-PNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, D)	Heat shock protein 75 kDa, mitochondrial, SpyCatcher	polymer	774	87094.6	2	UniProt (Q12931) Pfam (PF00183)	Homo sapiens (Human)	HSP 75,TNFR-associated protein 1,Tumor necrosis factor type 1 receptor-associated protein,TRAP-1
2	B, D (B, C)	Heat shock protein 75 kDa, mitochondrial, SpyTag, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (chimera)	polymer	829	93121.3	2	UniProt (Q12931) UniProt (P21912) Pfam (PF00183) Pfam (PF13085)	Homo sapiens (Human)	HSP 75,TNFR-associated protein 1,Tumor necrosis factor type 1 receptor-associated protein,TRAP-1,Iron-sulfur subunit of complex II,Ip, SdhB
3	E, H, K, N (A, B, D, C)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	4	Chemie (ANP)
4	F, I, L, O (A, B, D, C)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	G, J, M, P (A, B, D, C)	POTASSIUM ION	non-polymer		39.1	4	Chemie (K)

Sequence modifications

A, D: 60 - 704 (UniProt: Q12931)

PDB	External Database	Details
Gly 54	-	expression tag
Ile 55	-	expression tag
Asp 56	-	expression tag
Pro 57	-	expression tag
Phe 58	-	expression tag
Thr 59	-	expression tag
Gly 307	Arg 307	conflict

A, D: 705 - 827 (PDB: 7KLU)
B, C: 60 - 704 (UniProt: Q12931)

PDB	External Database	Details
Gly 54	-	expression tag
Ile 55	-	expression tag
Asp 56	-	expression tag
Pro 57	-	expression tag
Phe 58	-	expression tag
Thr 59	-	expression tag
Gly 307	Arg 307	conflict

B, C: 705 - 750 (PDB: 7KLU)
B, C: 751 - 882 (UniProt: P21912)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	360431.9
Non-Polymers*	Number of molecules	12
	Total formula weight	2278.4
All*	Total formula weight	362710.3

*Water molecules are not included.