7KLT

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59N mutant with pyruvate bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34161.2	6	UniProt (Q9PPB4) Pfam (PF00701)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	BB, G, HA, TA, U (E, A, C, D, B)	TETRAETHYLENE GLYCOL	non-polymer		194.2	5	Chemie (PG4)
3	CB, DB, H, I, IA... (E, A, C, F, B)	MAGNESIUM ION	non-polymer		24.3	10	Chemie (MG)
4	AA, BA, CA, EB, FB... (B, E, A, C, F...)	1,2-ETHANEDIOL	non-polymer		62.1	26	Chemie (EDO)
5	IB, N, PA, QB, YA (E, A, C, F, D)	TRIETHYLENE GLYCOL	non-polymer		150.2	5	Chemie (PGE)
6	AB, DA, EA, JB, O... (D, B, E, A, C...)	ACETATE ION	non-polymer		59.0	12	Chemie (ACT)
7	KB, R, RA, S (E, A, C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
8	FA, GA, SA, T (B, C, A)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
9	UB, VB, WB, XB, YB... (A, B, C, D, E...)	water	water		18.0	681	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 59	His 59	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	204967.3
Non-Polymers*	Number of molecules	66
	Total formula weight	5080.2
All*	Total formula weight	210047.5

*Water molecules are not included.