7KLQ

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59A mutant with pyruvate bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34118.2	6	UniProt (Q9PPB4) Pfam (PF00701) In PDB	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	A, B, D	TRIETHYLENE GLYCOL	non-polymer		150.2	4	Chemie (PGE)
3	F, A, B, C, D	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	6	Chemie (PEG)
4	E, A, B	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
6	F, A, B, D	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
7		water	water		18.0	761	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 59	His 59	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	204709.1
Non-Polymers*	Number of molecules	24
	Total formula weight	1949.3
All*	Total formula weight	206658.4

*Water molecules are not included.