7KLJ

Crystal structure of the WD-repeat domain of human KIF21A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Isoform 2 of Kinesin-like protein KIF21A	polymer	335	36751.6	2	UniProt (Q7Z4S6) Pfam (PF00400)	Homo sapiens (Human)	Kinesin-like protein KIF2,Renal carcinoma antigen NY-REN-62
2	C, H (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
3	D, E, F, G, I (A, B)	UNKNOWN ATOM OR ION	non-polymer			5	Chemie (UNX)
4	J, K (A, B)	water	water		18.0	548	Chemie (HOH)

Sequence modifications

A, B: 1337 - 1654 (UniProt: Q7Z4S6)

PDB	External Database	Details
Met 1319	-	expression tag
His 1320	-	expression tag
His 1321	-	expression tag
His 1322	-	expression tag
His 1323	-	expression tag
His 1324	-	expression tag
His 1325	-	expression tag
Ser 1326	-	expression tag
Ser 1327	-	expression tag
Gly 1328	-	expression tag
Arg 1329	-	expression tag
Glu 1330	-	expression tag
Asn 1331	-	expression tag
Leu 1332	-	expression tag
Tyr 1333	-	expression tag
Phe 1334	-	expression tag
Gln 1335	-	expression tag
Gly 1336	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73503.2
Non-Polymers*	Number of molecules	7
	Total formula weight	124.1
All*	Total formula weight	73627.4

*Water molecules are not included.