7KKQ
Structure of the catalytic domain of tankyrase 1 in complex with veliparib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Poly [ADP-ribose] polymerase | polymer | 213 | 24356.6 | 4 | UniProt (Q59FX0) Pfam (PF00644) UniProt (by SIFTS) (O95271) In PDB | Homo sapiens (Human) | PARP |
| 2 | A, B, C, D | (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium | non-polymer | 244.3 | 4 | Chemie (78P) | |||
| 3 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 833 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1104 - 1314 (UniProt: Q59FX0)
| PDB | External Database | Details |
|---|---|---|
| Gly 1102 | - | expression tag |
| Ser 1103 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 97426.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1238.8 | |
| All* | Total formula weight | 98665.1 |
