7KJZ
crystal structure of PLEKHA7 PH domain biding inositol-tetraphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pleckstrin homology domain-containing family A member 7 | polymer | 140 | 16057.3 | 2 | UniProt (Q6IQ23) Pfam (PF00169) | Homo sapiens (Human) | PH domain-containing family A member 7 |
| 2 | C, D (B) | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | non-polymer | 500.1 | 2 | Chemie (4IP) | |||
| 3 | E (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A, B: 164 - 298 (UniProt: Q6IQ23)
| PDB | External Database | Details |
|---|---|---|
| Gly 159 | - | expression tag |
| Pro 160 | - | expression tag |
| Leu 161 | - | expression tag |
| Gly 162 | - | expression tag |
| Ser 163 | - | expression tag |
| Lys 175 | Asp 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32114.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1062.2 | |
| All* | Total formula weight | 33176.9 |
