7KI4
Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, B, E) | Fusion glycoprotein F0 | polymer | 543 | 60028.1 | 3 | UniProt (Q9IH63) Pfam (PF00523) | Nipah virus | Protein F |
| 2 | B, E, H (L, C, F) | 12B2 Fab light chain | polymer | 214 | 23657.1 | 3 | Mus musculus (mouse) | ||
| 3 | C, F, I (H, D, G) | 12B2 heavy chain | polymer | 443 | 48630.8 | 3 | Mus musculus (mouse) | ||
| 4 | J, L, N, P, R... (I, K, N, P, R...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 5 | K, O, S (J, O, S) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | M, Q, U (M, Q, U) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 3 | In PDB GlyTouCan (G82348BZ) |
Sequence modifications
A, B, E: 1 - 487 (UniProt: Q9IH63)
| PDB | External Database | Details |
|---|---|---|
| Asp 305 | Asn 305 | conflict |
| Met 488 | - | expression tag |
| Lys 489 | - | expression tag |
| Gln 490 | - | expression tag |
| Ile 491 | - | expression tag |
| Glu 492 | - | expression tag |
| Asp 493 | - | expression tag |
| Lys 494 | - | expression tag |
| Ile 495 | - | expression tag |
| Glu 496 | - | expression tag |
| Glu 497 | - | expression tag |
| Ile 498 | - | expression tag |
| Leu 499 | - | expression tag |
| Ser 500 | - | expression tag |
| Lys 501 | - | expression tag |
| Ile 502 | - | expression tag |
| Tyr 503 | - | expression tag |
| His 504 | - | expression tag |
| Ile 505 | - | expression tag |
| Glu 506 | - | expression tag |
| Asn 507 | - | expression tag |
| Glu 508 | - | expression tag |
| Ile 509 | - | expression tag |
| Ala 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Ile 512 | - | expression tag |
| Lys 513 | - | expression tag |
| Lys 514 | - | expression tag |
| Leu 515 | - | expression tag |
| Ile 516 | - | expression tag |
| Gly 517 | - | expression tag |
| Glu 518 | - | expression tag |
| Ala 519 | - | expression tag |
| Pro 520 | - | expression tag |
| Gly 521 | - | expression tag |
| Gly 522 | - | expression tag |
| Ile 523 | - | expression tag |
| Glu 524 | - | expression tag |
| Gly 525 | - | expression tag |
| Arg 526 | - | expression tag |
| Lys 527 | - | expression tag |
| Leu 528 | - | expression tag |
| Lys 529 | - | expression tag |
| Glu 530 | - | expression tag |
| Thr 531 | - | expression tag |
| Ala 532 | - | expression tag |
| Ala 533 | - | expression tag |
| Ala 534 | - | expression tag |
| Lys 535 | - | expression tag |
| Phe 536 | - | expression tag |
| Glu 537 | - | expression tag |
| Arg 538 | - | expression tag |
| Gln 539 | - | expression tag |
| His 540 | - | expression tag |
| Met 541 | - | expression tag |
| Asp 542 | - | expression tag |
| Ser 543 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 396947.6 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 7476.9 | |
| All* | Total formula weight | 404424.6 |
