7KHY
Crystal structure of OXA-163 K73A in complex with meropenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 240 | 27725.4 | 1 | UniProt (F6KZJ2) Pfam (PF00905) | Enterobacter cloacae | OXA-163 |
| 2 | B (A) | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 385.5 | 1 | Chemie (MER) | |||
| 3 | C (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F, G (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | H (A) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A: 25 - 261 (UniProt: F6KZJ2)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| His 23 | - | expression tag |
| Met 24 | - | expression tag |
| Ala 73 | Lys 73 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27725.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 705.4 | |
| All* | Total formula weight | 28430.8 |
