7KHK
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX9486 (bezuclastinib) in the DFG-in state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mast/stem cell growth factor receptor Kit | polymer | 335 | 37984.1 | 2 | Pfam (PF07714) UniProt (by SIFTS) (P10721) | Homo sapiens (human) | |
| 2 | C, D (A, B) | 4,5-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-3-carboxamide | non-polymer | 331.4 | 2 | Chemie (WEJ) | |||
| 3 | E (A) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75968.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 662.7 | |
| All* | Total formula weight | 76630.9 |
