7KHJ

Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX8512 in the DFG-in state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Mast/stem cell growth factor receptor Kit	polymer	335	38026.1	2	Pfam (PF07714) UniProt (by SIFTS) (P10721) In PDB	Homo sapiens (Human)
2	A, B	2-phenyl-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine	non-polymer		260.3	2	Chemie (WEG)
3		water	water		18.0	36	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76052.3
Non-Polymers*	Number of molecules	2
	Total formula weight	520.6
All*	Total formula weight	76572.9

*Water molecules are not included.