7KG6
Structure of human PARG complexed with PARG-322
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Poly(ADP-ribose) glycohydrolase | polymer | 531 | 61020.4 | 1 | UniProt (Q86W56) Pfam (PF20811) Pfam (PF05028) In PDB | Homo sapiens (Human) | |
2 | A | 1-{2-[(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)sulfanyl]ethyl}piperidine-4-carboxylic acid | non-polymer | 367.4 | 1 | Chemie (WDG) | |||
3 | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence modifications
A: 448 - 976 (UniProt: Q86W56)
PDB | External Database | Details |
---|---|---|
Gly 446 | - | expression tag |
Ser 447 | - | expression tag |
Ala 616 | Lys 616 | engineered mutation |
Ala 617 | Gln 617 | engineered mutation |
Ala 618 | Lys 618 | engineered mutation |
Ala 688 | Glu 688 | engineered mutation |
Ala 689 | Lys 689 | engineered mutation |
Ala 690 | Lys 690 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 61020.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 367.4 | |
All* | Total formula weight | 61387.8 |