7KG4
Recombinant Beta-2-Glycoprotein I antibody recognition loop mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-2-glycoprotein 1 | polymer | 326 | 36169.3 | 2 | UniProt (P02749) Pfam (PF00084) Pfam (PF09014) | Homo sapiens (Human) | APC inhibitor,Activated protein C-binding protein,Anticardiolipin cofactor,Apolipoprotein H,Apo-H,Beta-2-glycoprotein I,Beta(2)GPI |
| 2 | C, E (C, E) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 2 | In PDB GlyTouCan (G47477HI) | |||
| 3 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 4 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | G, H, I (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, B: 1 - 326 (UniProt: P02749)
| PDB | External Database | Details |
|---|---|---|
| Ser 39 | Arg 58 | engineered mutation |
| Glu 40 | Gly 59 | engineered mutation |
| Val 42 | Met 61 | engineered mutation |
| Gly 43 | Arg 62 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72338.7 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2460.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 75462.6 |
