7KG2
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site and L-histidine bound at the allosteric site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34176.3 | 6 | UniProt (A0A2U0QMK8) Pfam (PF00701) UniProt (by SIFTS) (Q9PPB4) In PDB | Campylobacter jejuni | HTPA synthase |
2 | B, D, A, F, C... | 1,2-ETHANEDIOL | non-polymer | 62.1 | 38 | Chemie (EDO) | |||
3 | B, D, F, A, C... | MAGNESIUM ION | non-polymer | 24.3 | 14 | Chemie (MG) | |||
4 | B, D, F, C, A... | ACETATE ION | non-polymer | 59.0 | 15 | Chemie (ACT) | |||
5 | E, B, D, C, A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 8 | Chemie (PGE) | |||
6 | E, B, D, F, C... | HISTIDINE | non-polymer | 156.2 | 6 | Chemie (HIS) | |||
7 | D | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
8 | E, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
9 | water | water | 18.0 | 761 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 298 (UniProt: A0A2U0QMK8)
PDB | External Database | Details |
---|---|---|
Met -11 | - | expression tag |
Arg -10 | - | expression tag |
Gly -9 | - | expression tag |
Ser -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Lys 59 | His 59 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 205057.8 | |
Non-Polymers* | Number of molecules | 87 |
Total formula weight | 6447.7 | |
All* | Total formula weight | 211505.5 |