7KFW
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E (A, B, E) | Spike glycoprotein | polymer | 228 | 25467.7 | 3 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | C, F, H (C, F, H) | heavy chain of antibody C1A-B3 Fab | polymer | 225 | 23824.6 | 3 | Homo sapiens | ||
| 3 | D, G, I (D, G, L) | light chain of antibody C1A-B3 Fab | polymer | 214 | 23219.7 | 3 | Homo sapiens | ||
| 4 | J, K, L (A, B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 400 | Chemie (HOH) |
Sequence modifications
A, B, E: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 314 | - | expression tag |
| Ser 315 | - | expression tag |
| Gly 316 | - | expression tag |
| Ser 317 | - | expression tag |
| Gly 318 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 217536.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 218199.6 |
