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7KFN

Structure of Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA containing a 2'-deoxy Benner's Base Z opposite the edited base

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, D)
Double-stranded RNA-specific editase 1polymer40345005.42UniProt (P78563)
Pfam (PF02137)
Homo sapiens (Human)RNA-editing deaminase 1, RNA-editing enzyme 1, dsRNA adenosine deaminase
2B
(B)
Gli1 8AZ 23mer RNApolymer237415.41Homo sapiens
3C
(C)
Gli1 1W5 23mer RNApolymer237363.51Homo sapiens
4E, G
(A, D)
INOSITOL HEXAKISPHOSPHATEnon-polymer660.02Chemie (IHP)
5F, H
(A, D)
ZINC IONnon-polymer65.42Chemie (ZN)
6I, J, K, L
(A, B, C, D)
waterwater18.0252Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight104789.7
Non-Polymers*Number of molecules4
Total formula weight1450.9
All*Total formula weight106240.6
*Water molecules are not included.

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PDB entries from 2025-12-03

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