7KF3

Crystal structure of GDP-mannose 4,6-dehydratase from Brucella abortus (strain 2308) in complex with Guanosine-diphosphate-rhamnose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	GDP-mannose 4,6-dehydratase	polymer	369	42001.4	4	UniProt (Q2YMP3) Pfam (PF01370) In PDB	Brucella abortus (strain 2308)	GDP-D-mannose dehydratase
2	A, B, C, D	GUANOSINE-5'-DIPHOSPHATE-RHAMNOSE	non-polymer		589.3	4	Chemie (GDR)
3	A, B, C, D	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
4		water	water		18.0	569	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 362 (UniProt: Q2YMP3)

PDB	External Database	Details
Gly 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	168005.6
Non-Polymers*	Number of molecules	8
	Total formula weight	5331.0
All*	Total formula weight	173336.6

*Water molecules are not included.