7KEW

Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-43

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I (A, B, C)	Spike glycoprotein 1	polymer	343	38579.6	3	UniProt (A0A510C2V9) Pfam (PF01611) UniProt (by SIFTS) (B8XCN0)	Bundibugyo ebolavirus
2	B, F, J (G, H, I)	BDBV-43 Fab heavy chain	polymer	246	26233.7	3		Homo sapiens (human)
3	C, G, K (J, K, L)	BDBV-43 Fab light chain	polymer	232	25397.6	3		Homo sapiens (human)
4	D, H, L (D, E, F)	Envelope glycoprotein 2	polymer	177	19683.9	3	UniProt (B8XCN0) Pfam (PF22307)	Bundibugyo ebolavirus	Spike glycoprotein
5	M, N, Q (M, N, Q)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
6	O, P, R (O, P, R)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G22768VO)
7	S, T, U (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 312 (UniProt: A0A510C2V9)

PDB	External Database	Details
Ile 313	-	expression tag
Asp 314	-	expression tag
Ile 315	-	expression tag
Ser 316	-	expression tag
Glu 317	-	expression tag
Ser 318	-	expression tag
Thr 319	-	expression tag
Glu 320	-	expression tag
Pro 321	-	expression tag
Gly 322	-	expression tag
Pro 323	-	expression tag
Leu 324	-	expression tag
Thr 325	-	expression tag
Asn 326	-	expression tag
Thr 327	-	expression tag
Thr 328	-	expression tag
Arg 329	-	expression tag
Gly 330	-	expression tag
Ala 331	-	expression tag
Ala 332	-	expression tag
Asn 333	-	expression tag
Leu 334	-	expression tag
Leu 335	-	expression tag
Thr 336	-	expression tag
Gly 337	-	expression tag
Ser 338	-	expression tag
Arg 339	-	expression tag
Arg 340	-	expression tag
Thr 341	-	expression tag
Arg 342	-	expression tag
Arg 343	-	expression tag

D, E, F: 502 - 640 (UniProt: B8XCN0)

PDB	External Database	Details
Val 641	-	expression tag
Glu 642	-	expression tag
Val 643	-	expression tag
Asp 644	-	expression tag
Asp 645	-	expression tag
Asp 646	-	expression tag
Asp 647	-	expression tag
Lys 648	-	expression tag
Ala 649	-	expression tag
Gly 650	-	expression tag
Trp 651	-	expression tag
Ser 652	-	expression tag
His 653	-	expression tag
Pro 654	-	expression tag
Gln 655	-	expression tag
Phe 656	-	expression tag
Glu 657	-	expression tag
Lys 658	-	expression tag
Gly 659	-	expression tag
Gly 660	-	expression tag
Gly 661	-	expression tag
Ser 662	-	expression tag
Gly 663	-	expression tag
Gly 664	-	expression tag
Gly 665	-	expression tag
Ser 666	-	expression tag
Gly 667	-	expression tag
Gly 668	-	expression tag
Gly 669	-	expression tag
Ser 670	-	expression tag
Trp 671	-	expression tag
Ser 672	-	expression tag
His 673	-	expression tag
Pro 674	-	expression tag
Gln 675	-	expression tag
Phe 676	-	expression tag
Glu 677	-	expression tag
Lys 678	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	329684.3
Branched	Number of molecules	6
	Total formula weight	4005.7
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	334353.6

*Water molecules are not included.