7KEL

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34176.3	12	UniProt (A0A2U0QMK8) Pfam (PF00701) UniProt (by SIFTS) (Q9PPB4)	Campylobacter jejuni	HTPA synthase
2	AB, DC, GA, HA, JB... (E, I, C, F, J...)	TRIETHYLENE GLYCOL	non-polymer		150.2	10	Chemie (PGE)
3	BB, BD, CB, FC, GC... (E, L, I, C, F...)	ACETATE ION	non-polymer		59.0	19	Chemie (ACT)
4	DB, EB, JA, KA, P... (E, C, A, D)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
5	AA, AC, BA, BC, CA... (B, H, L, E, I...)	1,2-ETHANEDIOL	non-polymer		62.1	56	Chemie (EDO)
6	CC, GD, HD, OB, VC... (H, L, F, J, G)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	6	Chemie (PEG)
7	AD, EC, PB (L, I, G)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
8	ID, JD, KD, LD, MD... (A, B, C, D, E...)	water	water		18.0	1572	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 298 (UniProt: A0A2U0QMK8)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Lys 59	His 59	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	410115.5
Non-Polymers*	Number of molecules	100
	Total formula weight	7158.2
All*	Total formula weight	417273.7

*Water molecules are not included.