7KCZ

CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) IGG1 FC FRAGMENT- FC-GAMMA RECEPTOR III COMPLEX V158 MUTANT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, E (A, B, D, E)	IgG1 Fc	polymer	224	25143.4	4	UniProt (F6RL33) Pfam (PF07654)	Macaca mulatta (Rhesus macaque)
2	C, F (C, F)	Low affinity immunoglobulin gamma Fc region receptor III	polymer	192	21974.7	2	UniProt (A3RFZ7) Pfam (PF13895)	Macaca mulatta (Rhesus macaque)	IgG Fc receptor III,Fc-gamma RIII,FcRIII
3	G, H, J, K (G, H, J, K)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1463.3	4	In PDB GlyTouCan (G80858MF)
4	I (I)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
5	L (L)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
6	M, N, O, P (C, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
7	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	8	Chemie (HOH)

Sequence modifications

C, F: 0 - 191 (UniProt: A3RFZ7)

PDB	External Database	Details
Gln 38	Asn 56	engineered mutation
Val 158	Ile 176	engineered mutation
Gln 169	Asn 187	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	144523.0
Branched	Number of molecules	6
	Total formula weight	7334.8
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	152742.6

*Water molecules are not included.