7KCW
Crystal structure of S. aureus penicillin-binding protein 4 (PBP4) mutant (R200L) in complex with nafcillin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Penicillin-binding protein 4 | polymer | 367 | 41054.3 | 1 | UniProt (A0A0H2WY27) Pfam (PF00144) Pfam (PF00768) Pfam (PF09211) In PDB | Staphylococcus aureus (strain COL) | |
| 2 | A | (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | non-polymer | 416.5 | 1 | Chemie (NFF) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence modifications
A: 21 - 383 (UniProt: A0A0H2WY27)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Ser 18 | - | expression tag |
| His 19 | - | expression tag |
| Met 20 | - | expression tag |
| Leu 200 | Arg 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41054.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 666.1 | |
| All* | Total formula weight | 41720.4 |
