7KCO
ROR gamma in complex with SCR2 and compound 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nuclear receptor ROR-gamma | polymer | 248 | 28839.4 | 2 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | C, D (C, D) | Peptide GLU-LYS-HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP-SER | polymer | 13 | 1621.9 | 2 | UniProt (by SIFTS) (Q15596) | Homo sapiens | |
| 3 | E, F (A, B) | 1-[(2-chlorophenyl)methyl]-N-{[4-(methylsulfonyl)phenyl]methyl}-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-2'-carboxamide | non-polymer | 545.1 | 2 | Chemie (WB7) | |||
| 4 | G (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence modifications
A, B: 262 - 507 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Ser 260 | - | expression tag |
| Leu 261 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60922.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1182.3 | |
| All* | Total formula weight | 62105.0 |
