7KC5
X-ray structure of Lfa-1 I domain in complex with BMS-68852 collected at 273 K
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Integrin alpha-L | polymer | 184 | 20936.0 | 2 | UniProt (P20701) Pfam (PF00092) In PDB | Homo sapiens (Human) | CD11 antigen-like family member A,Leukocyte adhesion glycoprotein LFA-1 alpha chain,LFA-1A,Leukocyte function-associated molecule 1 alpha chain |
| 2 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | A, C | 6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl]pyridine-3-carboxylic acid | non-polymer | 536.4 | 2 | Chemie (BJZ) | |||
| 4 | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A, C: 128 - 309 (UniProt: P20701)
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | expression tag |
| Ser 127 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41871.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1121.3 | |
| All* | Total formula weight | 42993.3 |
