7KC4
Human WLS in complex with WNT8A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Protein Wnt-8a | polymer | 361 | 40052.4 | 1 | UniProt (Q9H1J5) Pfam (PF00110) | Homo sapiens (Human) | Protein Wnt-8d |
| 2 | B (B) | Protein wntless homolog | polymer | 567 | 65649.4 | 1 | UniProt (Q5T9L3) Pfam (PF21883) Pfam (PF06664) | Homo sapiens (Human) | Integral membrane protein GPR177,Protein evenness interrupted homolog,EVI,Putative NF-kappa-B-activating protein 373 |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D (C) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G42984ZU) | |||
| 5 | E (D) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 6 | F, G, H (B) | 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL | non-polymer | 747.0 | 3 | Chemie (DR9) | |||
| 7 | I (B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) |
Sequence modifications
D: 1 - 351 (UniProt: Q9H1J5)
B: 1 - 541 (UniProt: Q5T9L3)
| PDB | External Database | Details |
|---|---|---|
| Gly 352 | - | expression tag |
| Gly 353 | - | expression tag |
| Trp 354 | - | expression tag |
| Ser 355 | - | expression tag |
| His 356 | - | expression tag |
| Pro 357 | - | expression tag |
| Gln 358 | - | expression tag |
| Phe 359 | - | expression tag |
| Glu 360 | - | expression tag |
| Lys 361 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 542 | - | expression tag |
| Glu 543 | - | expression tag |
| Asn 544 | - | expression tag |
| Leu 545 | - | expression tag |
| Tyr 546 | - | expression tag |
| Phe 547 | - | expression tag |
| Gln 548 | - | expression tag |
| Ser 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| His 559 | - | expression tag |
| Asp 560 | - | expression tag |
| Tyr 561 | - | expression tag |
| Lys 562 | - | expression tag |
| Asp 563 | - | expression tag |
| Asp 564 | - | expression tag |
| Asp 565 | - | expression tag |
| Asp 566 | - | expression tag |
| Lys 567 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 105701.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1497.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2984.1 | |
| All* | Total formula weight | 110183.3 |
