7KC4
Human WLS in complex with WNT8A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Protein Wnt-8a | polymer | 361 | 40052.4 | 1 | UniProt (Q9H1J5) Pfam (PF00110) | Homo sapiens (Human) | Protein Wnt-8d |
| 2 | B (B) | Protein wntless homolog | polymer | 567 | 65649.4 | 1 | UniProt (Q5T9L3) Pfam (PF21883) Pfam (PF06664) | Homo sapiens (Human) | Integral membrane protein GPR177,Protein evenness interrupted homolog,EVI,Putative NF-kappa-B-activating protein 373 |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D (C) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G42984ZU) | |||
| 5 | E (D) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 6 | F, G, H (B) | 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL | non-polymer | 747.0 | 3 | Chemie (DR9) PubChem (21158790) PubChem (52927146) PubChem (49866918) PubChem (73746201) PubChem (5288113) PubChem (171936242) | |||
| 7 | I (B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (57163942) PubChem (45489984) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (65082) PubChem (124301053) PubChem (124302591) PubChem (363416) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (500055) PubChem (124914595) PubChem (124914596) PubChem (13301926) PubChem (13301927) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
D: 1 - 351 (UniProt: Q9H1J5)
B: 1 - 541 (UniProt: Q5T9L3)
| PDB | External Database | Details |
|---|---|---|
| Gly 352 | - | expression tag |
| Gly 353 | - | expression tag |
| Trp 354 | - | expression tag |
| Ser 355 | - | expression tag |
| His 356 | - | expression tag |
| Pro 357 | - | expression tag |
| Gln 358 | - | expression tag |
| Phe 359 | - | expression tag |
| Glu 360 | - | expression tag |
| Lys 361 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 542 | - | expression tag |
| Glu 543 | - | expression tag |
| Asn 544 | - | expression tag |
| Leu 545 | - | expression tag |
| Tyr 546 | - | expression tag |
| Phe 547 | - | expression tag |
| Gln 548 | - | expression tag |
| Ser 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| His 559 | - | expression tag |
| Asp 560 | - | expression tag |
| Tyr 561 | - | expression tag |
| Lys 562 | - | expression tag |
| Asp 563 | - | expression tag |
| Asp 564 | - | expression tag |
| Asp 565 | - | expression tag |
| Asp 566 | - | expression tag |
| Lys 567 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 105701.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1497.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2984.1 | |
| All* | Total formula weight | 110183.3 |
