7KC1
Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, C, G) | Hemagglutinin | polymer | 345 | 38515.6 | 3 | UniProt (L0HR89) Pfam (PF00509) | Influenza A virus | |
| 2 | B, F, J (B, D, I) | Fusion protein of Hemagglutinin and Envelope glycoprotein | polymer | 222 | 25259.1 | 3 | UniProt (A0A2P1E3C0) UniProt (M1E1E4) Pfam (PF00509) UniProt (by SIFTS) (L0HR89) | Influenza A virus | |
| 3 | C, G, K (H, E, J) | Fab heavy chain | polymer | 227 | 24292.3 | 3 | Homo sapiens (Human) | ||
| 4 | D, H, L (L, F, K) | Fab light chain | polymer | 206 | 22450.8 | 3 | Homo sapiens (Human) | ||
| 5 | M, N, O, Q, R... (M, N, O, Q, R...) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 9 | In PDB GlyTouCan (G22768VO) | |||
| 6 | P, T, X (P, T, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 7 | AA, BA, CA, DA, EA... (A, B, C, D, G...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
B, D, I: 1 - 176 (UniProt: A0A2P1E3C0)
B, D, I: 189 - 216 (UniProt: M1E1E4)
| PDB | External Database | Details |
|---|---|---|
| Ser 177 | - | linker |
| Gly 178 | - | linker |
| Arg 179 | - | linker |
| Leu 180 | - | linker |
| Val 181 | - | linker |
| Pro 182 | - | linker |
| Arg 183 | - | linker |
| Gly 184 | - | linker |
| Ser 185 | - | linker |
| Pro 186 | - | linker |
| Gly 187 | - | linker |
| Ser 188 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 331553.4 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 9957.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 344828.6 |
