7KC1

Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, G	Hemagglutinin	polymer	345	38515.6	3	UniProt (L0HR89) Pfam (PF00509) In PDB	Influenza A virus
2	B, D, I	Fusion protein of Hemagglutinin and Envelope glycoprotein	polymer	222	25259.1	3	UniProt (A0A2P1E3C0) UniProt (M1E1E4) Pfam (PF00509) UniProt (by SIFTS) (L0HR89) In PDB	Influenza A virus
3	H, E, J	Fab heavy chain	polymer	227	24292.3	3		Homo sapiens (Human)
4	L, F, K	Fab light chain	polymer	206	22450.8	3		Homo sapiens (Human)
5	M, N, O, Q, R...	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	9	In PDB GlyTouCan (G22768VO)
6	P, T, X	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	3	In PDB GlyTouCan (G15407YE)
7	A, B, C, D, G...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	15	Chemie (NAG)

Sequence modifications

B, D, I: 1 - 176 (UniProt: A0A2P1E3C0)

PDB	External Database	Details
Ser 177	-	linker
Gly 178	-	linker
Arg 179	-	linker
Leu 180	-	linker
Val 181	-	linker
Pro 182	-	linker
Arg 183	-	linker
Gly 184	-	linker
Ser 185	-	linker
Pro 186	-	linker
Gly 187	-	linker
Ser 188	-	linker

B, D, I: 189 - 216 (UniProt: M1E1E4)

PDB	External Database	Details
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	331553.4
Branched	Number of molecules	12
	Total formula weight	9957.0
Non-Polymers*	Number of molecules	15
	Total formula weight	3318.1
All*	Total formula weight	344828.6

*Water molecules are not included.