7KBS
Estrogen Receptor Alpha Ligand Binding Domain in Complex with Raloxifene
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Estrogen receptor | polymer | 263 | 30171.1 | 2 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (Human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
2 | A, B | RALOXIFENE | non-polymer | 473.6 | 2 | Chemie (RAL) | |||
3 | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
A, B: 307 - 554 (UniProt: P03372)
PDB | External Database | Details |
---|---|---|
His 292 | - | expression tag |
His 293 | - | expression tag |
His 294 | - | expression tag |
His 295 | - | expression tag |
His 296 | - | expression tag |
His 297 | - | expression tag |
Glu 298 | - | expression tag |
Asn 299 | - | expression tag |
Leu 300 | - | expression tag |
Tyr 301 | - | expression tag |
Phe 302 | - | expression tag |
Gln 303 | - | expression tag |
Ser 304 | - | expression tag |
Met 305 | - | expression tag |
Ser 306 | - | expression tag |
Ser 381 | Cys 381 | engineered mutation |
Ser 417 | Cys 417 | engineered mutation |
Ser 530 | Cys 530 | engineered mutation |
Ser 536 | Leu 536 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 60342.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 947.2 | |
All* | Total formula weight | 61289.4 |