7KBG
Structure of Human HDAC2 in complex with a 2-substituted benzamide inhibitor (compound 20)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone deacetylase 2 | polymer | 376 | 43062.0 | 3 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (Human) | HD2 |
| 2 | D, O, Y (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | AA, E, F, P, Q... (C, A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | BA, CA, DA, EA, G... (C, A, B) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 5 | FA, GA, K, L, M... (C, A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 7 | Chemie (PEG) | |||
| 6 | IA, N, W (C, A, B) | N-{(1S)-5-[(2-fluoro-6-hydroxybenzene-1-carbonyl)amino]-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]pentyl}-1,3-thiazole-5-carboxamide | non-polymer | 543.6 | 3 | Chemie (WBA) | |||
| 7 | X (C) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 8 | HA (C) | 2,5-dichloro-1H-benzimidazole | non-polymer | 187.0 | 1 | Chemie (WBD) | |||
| 9 | JA, KA, LA (A, B, C) | water | water | 18.0 | 1126 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 129186.0 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 4132.2 | |
| All* | Total formula weight | 133318.2 |
