7KAI
Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation 1 (C1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein transport protein SEC61 | polymer | 480 | 52978.1 | 1 | UniProt (P32915) Pfam (PF10559) Pfam (PF00344) | Saccharomyces cerevisiae BY4741 | Sec61 complex subunit SEC61,Sec61 complex subunit alpha |
| 2 | B (C) | Protein transport protein SSS1 | polymer | 80 | 8958.6 | 1 | UniProt (P35179) Pfam (PF00584) | Saccharomyces cerevisiae BY4741 | Sec61 complex subunit SSS1,Sec61 complex subunit gamma,Ssh1 complex subunit SSS1,Ssh1 complex subunit gamma |
| 3 | C (B) | Protein transport protein SBH1 | polymer | 82 | 8723.2 | 1 | UniProt (P52870) Pfam (PF03911) | Saccharomyces cerevisiae BY4741 | Sec61 complex subunit SBH1,Sec61 complex subunit beta |
| 4 | D (D) | Protein translocation protein SEC63 | polymer | 694 | 77933.7 | 1 | UniProt (P14906) Pfam (PF00226) | Saccharomyces cerevisiae BY4741 | Protein NPL1,Sec62/63 complex 73 kDa subunit |
| 5 | E (E) | Translocation protein SEC66 | polymer | 206 | 24263.9 | 1 | UniProt (P33754) Pfam (PF09802) | Saccharomyces cerevisiae BY4741 | Protein HSS1,Sec62/63 complex 31.5 kDa subunit |
| 6 | F (F) | Translocation protein SEC72 | polymer | 193 | 21631.1 | 1 | UniProt (P39742) | Saccharomyces cerevisiae BY4741 | Sec62/63 complex 23 kDa subunit,p23 |
| 7 | G (G) | Protein transport protein Sec62 | polymer | 56 | 4783.9 | 1 | Saccharomyces cerevisiae BY4741 |
Sequence modifications
D: 2 - 663 (UniProt: P14906)
| PDB | External Database | Details |
|---|---|---|
| Gly -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ala 664 | - | expression tag |
| Gly 665 | - | expression tag |
| Gly 666 | - | expression tag |
| Ala 667 | - | expression tag |
| Thr 668 | - | expression tag |
| Thr 669 | - | expression tag |
| Ala 670 | - | expression tag |
| Ser 671 | - | expression tag |
| Gly 672 | - | expression tag |
| Thr 673 | - | expression tag |
| Gly 674 | - | expression tag |
| Glu 675 | - | expression tag |
| Asn 676 | - | expression tag |
| Leu 677 | - | expression tag |
| Tyr 678 | - | expression tag |
| Phe 679 | - | expression tag |
| Gln 680 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 199272.5 | |
| All* | Total formula weight | 199272.5 |
