7K9A
Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 303 | 33475.0 | 2 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | C, J (A, C) | N-hydroxy-N-[(1S)-2-{5-[(4-{[2-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)ethynyl]-1H-benzotriazol-1-yl}-1-(methylsulfanyl)ethyl]formamide | non-polymer | 462.5 | 2 | Chemie (W4P) | |||
| 3 | D, M (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F, K, L (A, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | G (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | H, N (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | I (C) | N-hydroxy-N-[(1R)-2-{5-[(4-{[2-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)ethynyl]-1H-benzotriazol-1-yl}-1-(methylsulfanyl)ethyl]formamide | non-polymer | 462.5 | 1 | Chemie (W8P) | |||
| 8 | O, P (A, C) | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66950.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2157.0 | |
| All* | Total formula weight | 69107.1 |
