7K93

DENV2 NS1 in complex with neutralizing 2B7 single chain Fab variable region (scFv)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Non-structural protein 1	polymer	376	42674.2	4	UniProt (D0EPS0) Pfam (PF00948) UniProt (by SIFTS) (P29990)	Dengue virus 2
2	E, F, G, H (E, G, I, K)	2B7 single chain fab variable region	polymer	251	26719.6	4		Mus musculus (Mouse)	scFv
3	I, J, K, L (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

A, B, C, D: 0 - 352 (UniProt: D0EPS0)

PDB	External Database	Details
Ala -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	277575.3
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	278460.1

*Water molecules are not included.