7K87

The crystal structure of the 2009 H1N1 PA endonuclease in complex with SJ000986436

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein PA-X	polymer	197	23136.3	1	UniProt (A0A4D6EED0) UniProt (C6H0Y9) Pfam (PF00603) In PDB	Influenza A virus
2	A	Hexa Vinylpyrrolidone K15	non-polymer		668.9	1	Chemie (QQ4)
3	A	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
4	A	2-(2,6-difluorophenyl)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide	non-polymer		402.4	1	Chemie (W5V)
5		water	water		18.0	43	Chemie (HOH)

Sequence modifications

A: 1 - 50 (UniProt: A0A4D6EED0)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Gly 51	-	linker
Gly 52	-	linker
Ser 53	-	linker

A: 73 - 196 (UniProt: C6H0Y9)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23136.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1181.1
All*	Total formula weight	24317.4

*Water molecules are not included.