7K5Z

Crystal Structure of Argininosuccinate synthase from Legionella pneumophila Philadelphia 1 in complex with ANPPNP and a substrate analogue Arginine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Argininosuccinate synthase	polymer	413	46069.5	4	UniProt (Q5ZY78) Pfam (PF00764) Pfam (PF20979) In PDB	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	Citrulline--aspartate ligase, LepnA.00809.a
2	A, D, B, C	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	4	Chemie (ANP)
3	A, D, B, C	ARGININE	non-polymer		175.2	4	Chemie (ARG)
4	A, D, B, C	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	C, D, A, B	1,2-ETHANEDIOL	non-polymer		62.1	20	Chemie (EDO)
6	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
7		water	water		18.0	1590	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 405 (UniProt: Q5ZY78)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	184277.9
Non-Polymers*	Number of molecules	33
	Total formula weight	4123.2
All*	Total formula weight	188401.1

*Water molecules are not included.