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7K42

Crystal structure of the second bromodomain (BD2) of human TAF1 bound to dioxane

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transcription initiation factor TFIID subunit 1polymer13715882.82UniProt (P21675)
Pfam (PF00439)
Homo sapiens (Human)Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250
2C, Q
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
3D, R
(A, B)
1,4-DIETHYLENE DIOXIDEnon-polymer88.12Chemie (DIO)
4AA, BA, E, F, G...
(B, A)
1,2-ETHANEDIOLnon-polymer62.122Chemie (EDO)
5CA, DA
(A, B)
waterwater18.0321Chemie (HOH)
Sequence modifications
A, B: 1501 - 1635 (UniProt: P21675)
PDBExternal DatabaseDetails
Ser 1499-expression tag
Met 1500-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight31765.6
Non-Polymers*Number of molecules26
Total formula weight1733.8
All*Total formula weight33499.5
*Water molecules are not included.

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PDB entries from 2026-01-21

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