7K3P

The structure of the UDP-Glc/GlcNAc 4-epimerase from the human pathogen Campylobacter jejuni

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	UDP-glucose 4-epimerase	polymer	344	38361.5	2	UniProt (Q0P9C3) Pfam (PF01370)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
2	C, H (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D, E, F, I, J... (A, B)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
4	G, M (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
5	N, O (A, B)	water	water		18.0	167	Chemie (HOH)

Sequence modifications

A, B: 2 - 328 (UniProt: Q0P9C3)

PDB	External Database	Details
Met -15	-	initiating methionine
Gly -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Gly -5	-	expression tag
Leu -4	-	expression tag
Val -3	-	expression tag
Pro -2	-	expression tag
Arg -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Ala 45	Gln 45	engineered mutation
Ala 46	Lys 46	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76723.1
Non-Polymers*	Number of molecules	11
	Total formula weight	2089.6
All*	Total formula weight	78812.7

*Water molecules are not included.