7K3B
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation C, central helices splay
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin | polymer | 345 | 37948.8 | 3 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 2 | B, D, F (B, D, F) | Hemagglutinin | polymer | 254 | 28947.5 | 3 | UniProt (C7RWD9) Pfam (PF00509) UniProt (by SIFTS) (Q91MA7) | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 3 | G, I, K (G, I, K) | antibody Fab light chain | polymer | 219 | 23112.4 | 3 | Homo sapiens (Human) | ||
| 4 | H, J, L (H, J, L) | antibody Fab heavy chain | polymer | 235 | 25278.6 | 3 | Homo sapiens (Human) | ||
| 5 | M, P, S (M, P, S) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 6 | N, Q, T (N, Q, T) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 7 | O, R, U (O, R, U) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 3 | In PDB GlyTouCan (G61846BY) | |||
| 8 | AA, V, W, X, Y... (E, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
B, D, F: 1 - 221 (UniProt: C7RWD9)
| PDB | External Database | Details |
|---|---|---|
| Ser 222 | - | expression tag |
| Met 223 | - | expression tag |
| Gly 224 | - | expression tag |
| Trp 225 | - | expression tag |
| Ser 226 | - | expression tag |
| His 227 | - | expression tag |
| Pro 228 | - | expression tag |
| Gln 229 | - | expression tag |
| Phe 230 | - | expression tag |
| Glu 231 | - | expression tag |
| Lys 232 | - | expression tag |
| Gly 233 | - | expression tag |
| Gly 234 | - | expression tag |
| Gly 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Arg 237 | - | expression tag |
| Gly 238 | - | expression tag |
| Gly 239 | - | expression tag |
| Ser 240 | - | expression tag |
| Gly 241 | - | expression tag |
| Gly 242 | - | expression tag |
| Gly 243 | - | expression tag |
| Ser 244 | - | expression tag |
| Trp 245 | - | expression tag |
| Ser 246 | - | expression tag |
| His 247 | - | expression tag |
| Pro 248 | - | expression tag |
| Gln 249 | - | expression tag |
| Phe 250 | - | expression tag |
| Glu 251 | - | expression tag |
| Lys 252 | - | expression tag |
| Gly 253 | - | expression tag |
| Phe 254 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 345862.1 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 8197.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 355386.7 |
