7K3A
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation B, fusion peptide release
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | Hemagglutinin | polymer | 345 | 37948.8 | 3 | UniProt (Q91MA7) Pfam (PF00509) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
2 | B, D, F | Hemagglutinin | polymer | 254 | 28947.5 | 3 | UniProt (C7RWD9) Pfam (PF00509) UniProt (by SIFTS) (Q91MA7) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
3 | G, I, K | antibody Fab light chain | polymer | 219 | 23112.4 | 3 | Homo sapiens (Human) | ||
4 | H, J, L | antibody Fab heavy chain | polymer | 235 | 25278.6 | 3 | Homo sapiens (Human) | ||
5 | M, P, S | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
6 | N, Q, T | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
7 | O, R, U | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 3 | In PDB GlyTouCan (G61846BY) | |||
8 | D, E, F, A, B... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
B, D, F: 1 - 221 (UniProt: C7RWD9)
PDB | External Database | Details |
---|---|---|
Ser 222 | - | expression tag |
Met 223 | - | expression tag |
Gly 224 | - | expression tag |
Trp 225 | - | expression tag |
Ser 226 | - | expression tag |
His 227 | - | expression tag |
Pro 228 | - | expression tag |
Gln 229 | - | expression tag |
Phe 230 | - | expression tag |
Glu 231 | - | expression tag |
Lys 232 | - | expression tag |
Gly 233 | - | expression tag |
Gly 234 | - | expression tag |
Gly 235 | - | expression tag |
Ala 236 | - | expression tag |
Arg 237 | - | expression tag |
Gly 238 | - | expression tag |
Gly 239 | - | expression tag |
Ser 240 | - | expression tag |
Gly 241 | - | expression tag |
Gly 242 | - | expression tag |
Gly 243 | - | expression tag |
Ser 244 | - | expression tag |
Trp 245 | - | expression tag |
Ser 246 | - | expression tag |
His 247 | - | expression tag |
Pro 248 | - | expression tag |
Gln 249 | - | expression tag |
Phe 250 | - | expression tag |
Glu 251 | - | expression tag |
Lys 252 | - | expression tag |
Gly 253 | - | expression tag |
Phe 254 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 345862.1 | |
Branched | Number of molecules | 9 |
Total formula weight | 8197.4 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1990.9 | |
All* | Total formula weight | 356050.3 |