7K2W
Crystal structure of CTX-M-14 E166A/K234R Beta-lactamase in complex with hydrolyzed cefotaxime
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase | polymer | 261 | 27685.2 | 1 | UniProt (A0A2H4FY00) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (Q9L5C7) In PDB | Escherichia coli | |
| 2 | A | CEFOTAXIME, C3' cleaved, open, bound form | non-polymer | 397.4 | 1 | Chemie (CEF) | |||
| 3 | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence modifications
A: 27 - 289 (UniProt: A0A2H4FY00)
| PDB | External Database | Details |
|---|---|---|
| Asn 31 | Gln 35 | conflict |
| Ala 166 | Glu 169 | engineered mutation |
| Asp 240 | Gly 242 | conflict |
| Unk 253 | - | insertion |
| Asn 254 | Gln 255 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27685.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 397.4 | |
| All* | Total formula weight | 28082.6 |
