7K2R
Kelch domain of human KEAP1 bound to Nrf2-based cyclic peptide, c[LhA-DEETGE]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Kelch-like ECH-associated protein 1 | polymer | 290 | 31743.5 | 2 | UniProt (Q14145) Pfam (PF01344) | Homo sapiens (Human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | C (P) | B3A-ASP-PRO-GLU-THR-GLY-GLU | polymer | 7 | 731.7 | 1 | Homo sapiens | ||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | E, F, G (B, A, P) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
B, A: 325 - 614 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Ala 540 | Glu 540 | conflict |
| Ala 542 | Glu 542 | conflict |
| Ser 613 | Cys 613 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 64218.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 64314.8 |
