7K2R
Kelch domain of human KEAP1 bound to Nrf2-based cyclic peptide, c[LhA-DEETGE]
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Kelch-like ECH-associated protein 1 | polymer | 290 | 31743.5 | 2 | UniProt (Q14145) Pfam (PF01344) In PDB | Homo sapiens (Human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
2 | P | B3A-ASP-PRO-GLU-THR-GLY-GLU | polymer | 7 | 731.7 | 1 | Homo sapiens | ||
3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
B, A: 325 - 614 (UniProt: Q14145)
PDB | External Database | Details |
---|---|---|
Ala 540 | Glu 540 | conflict |
Ala 542 | Glu 542 | conflict |
Ser 613 | Cys 613 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 64218.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 96.1 | |
All* | Total formula weight | 64314.8 |