7K2E
Kelch domain of human KEAP1 bound to Nrf2-based cyclic peptide, c[GDEETGE]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kelch-like ECH-associated protein 1 | polymer | 301 | 33005.9 | 2 | UniProt (Q14145) Pfam (PF01344) | Homo sapiens (Human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | C (P) | GLY-ASP-GLU-GLU-THR-GLY-GLU | polymer | 7 | 735.7 | 1 | UniProt (by SIFTS) (Q16236) | Homo sapiens | |
| 3 | D, E, F (A, B, P) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A, B: 324 - 624 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Ala 540 | Glu 540 | conflict |
| Ala 542 | Glu 542 | conflict |
| Ser 613 | Cys 613 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66747.5 | |
| All* | Total formula weight | 66747.5 |
