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7K0Q

Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine palmitoyltransferase 1polymer47352806.81UniProt (O15269)
Pfam (PF00155)
Homo sapiens (Human)Long chain base biosynthesis protein 1,LCB 1,Serine-palmitoyl-CoA transferase 1,SPT1
2B
(B)
Serine palmitoyltransferase 2polymer56263004.21UniProt (O15270)
Pfam (PF00155)
Homo sapiens (Human)Long chain base biosynthesis protein 2,LCB 2,Long chain base biosynthesis protein 2a,LCB2a,Serine-palmitoyl-CoA transferase 2,SPT 2
3C
(C)
Serine palmitoyltransferase small subunit Apolymer718471.11UniProt (Q969W0)
Pfam (PF11779)
Homo sapiens (Human)Small subunit of serine palmitoyltransferase A,ssSPTa
4D
(D)
ORM1-like protein 3polymer15317512.61UniProt (Q8N138)
Pfam (PF04061)
Homo sapiens (Human)
5E
(B)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.11Chemie (PLP)
6F
(B)
Myriocinnon-polymer401.51Chemie (VRP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight141794.6
Non-Polymers*Number of molecules2
Total formula weight648.7
All*Total formula weight142443.3
*Water molecules are not included.

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PDB entries from 2024-11-06

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