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7K0L

Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine palmitoyltransferase 1polymer47352806.81UniProt (O15269)
Pfam (PF00155)
Homo sapiens (Human)Long chain base biosynthesis protein 1,LCB 1,Serine-palmitoyl-CoA transferase 1,SPT1
2B
(B)
Serine palmitoyltransferase 2polymer56263004.21UniProt (O15270)
Pfam (PF00155)
Homo sapiens (Human)Long chain base biosynthesis protein 2,LCB 2,Long chain base biosynthesis protein 2a,LCB2a,Serine-palmitoyl-CoA transferase 2,SPT 2
3C
(C)
Serine palmitoyltransferase small subunit Apolymer718471.11UniProt (Q969W0)
Pfam (PF11779)
Homo sapiens (Human)Small subunit of serine palmitoyltransferase A,ssSPTa
4D
(B)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.11Chemie (PLP)
PubChem (1051)
5E
(B)
Myriocinnon-polymer401.51Chemie (VRP)
PubChem (25233002)
PubChem (25791048)
PubChem (42608356)
PubChem (92280002)
PubChem (6299165)
PubChem (57024517)
PubChem (59118721)
PubChem (71772027)
PubChem (73707382)
PubChem (90934364)
PubChem (121989)
PubChem (124298613)
PubChem (301119)
PubChem (124304302)
PubChem (124304303)
PubChem (124554606)
PubChem (6184440)
PubChem (6438394)
PubChem (9978415)
PubChem (137705538)
PubChem (139031919)
PubChem (162904700)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight124282.0
Non-Polymers*Number of molecules2
Total formula weight648.7
All*Total formula weight124930.7
*Water molecules are not included.

253795

PDB entries from 2026-05-20

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