7JZJ

Crystal structure demonstrating CTD-CTD interactions of Zaire Ebola virus VP40 dimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Matrix protein VP40	polymer	297	32229.1	4	UniProt (Q05128) Pfam (PF07447)	Zaire ebolavirus (strain Mayinga-76) (ZEBOV)	Ebola VP40,eVP40,Membrane-associated protein VP40
2	E, F, G (A, B, D)	PENTAETHYLENE GLYCOL	non-polymer		238.3	3	Chemie (1PE)
3	H, I, J, K (A, B, C, D)	water	water		18.0	69	Chemie (HOH)

Sequence modifications

A, B, C, D: 43 - 326 (UniProt: Q05128)

PDB	External Database	Details
Met 30	-	initiating methionine
Ala 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
Val 38	-	expression tag
Asp 39	-	expression tag
Asp 40	-	expression tag
Asp 41	-	expression tag
Asp 42	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	128916.5
Non-Polymers*	Number of molecules	3
	Total formula weight	714.8
All*	Total formula weight	129631.4

*Water molecules are not included.