7JYT
hALK in complex with 3-(3-methyl-1H-pyrazol-5-yl)pyridine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ALK tyrosine kinase receptor | polymer | 322 | 36045.4 | 1 | UniProt (Q9UM73) Pfam (PF07714) In PDB | Homo sapiens (Human) | Anaplastic lymphoma kinase |
| 2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | A | 3-(3-methyl-1H-pyrazol-5-yl)pyridine | non-polymer | 159.2 | 1 | Chemie (VRM) | |||
| 4 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 1090 - 1406 (UniProt: Q9UM73)
| PDB | External Database | Details |
|---|---|---|
| Gly 1085 | - | expression tag |
| Ala 1086 | - | expression tag |
| Met 1087 | - | expression tag |
| Gly 1088 | - | expression tag |
| Ser 1089 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36045.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 251.3 | |
| All* | Total formula weight | 36296.7 |
