7JYN

Solution NMR structure of human Brd3 ET complexed with NSD3(148-184) peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bromodomain-containing protein 3	polymer	96	11264.5	1	UniProt (Q15059) Pfam (PF17035) In PDB	Homo sapiens (Human)	RING3-like protein
2	B	Histone-lysine N-methyltransferase NSD3	polymer	39	4329.8	1	UniProt (Q9BZ95) In PDB	Homo sapiens (Human)	Nuclear SET domain-containing protein 3,Protein whistle,WHSC1-like 1 isoform 9 with methyltransferase activity to lysine,Wolf-Hirschhorn syndrome candidate 1-like protein 1,WHSC1-like protein 1

Sequence modifications

A: 10 - 96 (UniProt: Q15059)

PDB	External Database	Details
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
Ser 7	-	expression tag
His 8	-	expression tag
Met 9	-	expression tag

B: 148 - 184 (UniProt: Q9BZ95)

PDB	External Database	Details
Glu 146	-	expression tag
Phe 147	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	15594.4
All*	Total formula weight	15594.4

*Water molecules are not included.