7JXY
Structure of TTBK1 kinase domain in complex with Compound 18
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tau-tubulin kinase 1 | polymer | 332 | 37883.6 | 2 | UniProt (Q5TCY1) Pfam (PF00069) In PDB | Homo sapiens (Human) | Brain-derived tau kinase |
| 2 | A, B | (3S)-1-[1-(2-aminopyrimidin-4-yl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-3-methylpent-1-yn-3-ol | non-polymer | 308.3 | 2 | Chemie (VSY) | |||
| 3 | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A, B: 15 - 343 (UniProt: Q5TCY1)
| PDB | External Database | Details |
|---|---|---|
| Gly 12 | - | expression tag |
| His 13 | - | expression tag |
| Met 14 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75767.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 616.7 | |
| All* | Total formula weight | 76383.8 |
