7JXT

Ovine COX-1 in complex with the subtype-selective derivative 2a

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Prostaglandin G/H synthase 1	polymer	553	63812.2	2	UniProt (P05979) Pfam (PF03098)	Ovis aries (Sheep)	Cyclooxygenase-1,COX-1,Prostaglandin H2 synthase 1,PHS 1,Prostaglandin-endoperoxide synthase 1
2	C, D, E, F, G... (E, F, G, H, I...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
3	I, K (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
4	J, L (A, B)	2-[4,5-bis(2-chlorophenyl)-1H-imidazol-2-yl]-6-(prop-2-en-1-yl)phenyl methoxyacetate	non-polymer		493.4	2	Chemie (W8M)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	127624.4
Branched	Number of molecules	6
	Total formula weight	2546.4
Non-Polymers*	Number of molecules	4
	Total formula weight	2219.7
All*	Total formula weight	132390.5

*Water molecules are not included.